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  • Antidepressant treatment with fluoxetine during pregnancy and lactation modulates the gut microbiome and metabolome in a rat model relevant to depression
    UMB Dataset

    Authors
    Anouschka S. Ramsteijn
    Eldin Jašarević
    Danielle J. Houwing
    Tracy L. Bale
    1 more author(s)...
    Description

    Data and figures are provided on the effects of fluoxetine, a selective serotin reuptake inhibitor (SSRI) antidepressant, on the gut microbiome and metabolome in a rat model to better understand the effect of this drug on women during gestation and lactation. Throughout pregnancy and lactation, female rats received the SSRI fluoxetine or vehicle. High resolution 16S ribosomal RNA marker gene sequencing and targeted metabolic analysis were used to assess the fecal microbiome and metabolic availability, respectively.

    Subject
    Antidepressive Agents
    Lactation
    Pregnancy
    Geographic Coverage
    Netherlands
    Access Rights
    Free to All
  • University of Maryland Medicine Biorepository
    UMB Dataset

    Alternate Title(s)
    UMM Biorepository, University of Maryland Genetics BIObank
    Description

    The UMM Biorepository is a resource building effort that includes banking of blood samples from UMMS patients as well as collections of various biospecimens from collaborating UM researchers. State-of-the-art robotic freezer and liquidhandling equipment offer a secure and managed environment for biospecimen processing, storage and distribution. Data connected to the samples is obtained through the electronic health record and/or study-specific data collection, allowing for multi-disciplinary research that can impact a range of health issues. Access to data and biospecimens is dependent upon specific study requirements.

    Subject
    Biological Specimen Banks
    Access Rights
    Permission subject to IRB approval
    Application Required
    Restricted to qualified University of Maryland investigators
    Local Experts
    Alan R. Shuldiner
    Coleen M. Damcott
  • National Health and Nutrition Examination Survey (NHANES)

    Alternate Title(s)
    NHANES
    Description

    The National Health and Nutrition Examination Survey (NHANES) is a program of studies designed to assess the health and nutritional status of adults and children in the United States. Participants are selected via a random sampling method. The survey is unique in that it combines interviews and physical examinations. The NHANES interview includes demographic, socioeconomic, dietary, and health-related questions. The examination component consists of medical, dental, and physiological measurements, as well as laboratory tests administered by highly trained medical personnel.

    Subject
    Health Status Indicators
    Population Health
    Geographic Coverage
    United States
    Access Rights
    Free to All
    Local Experts
    Alan R. Shuldiner
    Braxton C. Mitchell
    Gulam Muhammed Al Kibria
    Marc C. Hochberg
    Michael Miller
    Michelle D. Shardell
    Odessa R. Addison
    Rebecca M. Brotman
    Reese Crispen
    Samer S. El-Kamary
    Yan Wang
  • Health Outcomes and Measures of the Environment (HOME)

    Alternate Title(s)
    HOME
    Description

    The Health Outcomes and Measures of the Environment (HOME) Study, a prospective pregnancy and birth cohort in the greater Cincinnati OH metropolitan area, was established to determine whether early life environmental chemical exposures influence children’s health. Data include longitudinal and repeated measures of chemical exposures and child health beginning in the gestational age of 16.0 weeks with follow ups until 8 years of age. This includes 100+ environmental chemical exposures measured in women and children, as well as repeated measures of child neurodevelopment, anthropometry, respiratory and allergy outcomes, and injuries.

    Subject
    Child Health
    Environmental Exposure
    Geographic Coverage
    Ohio
    Access Rights
    Access via email request to designated investigators
    Local Experts
    Adam Spanier
    Erika Friedmann
    Robyn Gilden