UMB Data Catalog
A project of the Health Sciences and Human Services LibraryRefinement of a Live Attenuated Salmonella enterica Serovat Newport Vaccine with Improved Safety
UMB Dataset
UID: 207
- Description
- Non-typhoidal Salmonella (NTS) is responsible for approximately 93 million cases of gastroenteritis annually. Little research has been directed towards a development of vaccines against Salmonella serogroups O:6,7 or O:8. Researchers constructed a live attenuated serogroup O:8 vaccine, CVS 1979, by deleting guaBA, htrA, and aroA from the genome of S. Newport. Over the course of 6 weeks, 6 to 8-week-old female BALB/c mice were immunized with live attenuated S. Newport vaccine CVD 1979 or sterile phosphate buffered saline (PBS) three times. Four weeks after the last immunization, mice were challenged intraperitoneally (i.p.) with wild-type Salmonella strains to assess the homologous and heterologous protection elicited by the live attenuated S. Newport vaccine CVD 1979.
Female
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Access via Article
datatables
Access via Supplementary materialUnmodified Western bots
- Access Restrictions
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Unrestricted access
- Access Instructions
- The data presented in this study are contained within the article and supplementary material.
- Associated Publications
- Data Type
- Equipment Used
- Software Used
- Study Type
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Interventional
- Dataset Format(s)
- Dataset Size
- 161kb
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