UMB Data Catalog
A project of the Health Sciences and Human Services LibraryAntidepressant treatment with fluoxetine during pregnancy and lactation modulates the gut microbiome and metabolome in a rat model relevant to depression
UMB Dataset
UID: 106
- Description
- Data and figures are provided on the effects of fluoxetine, a selective serotin reuptake inhibitor (SSRI) antidepressant, on the gut microbiome and metabolome in a rat model to better understand the effect of this drug on women during gestation and lactation. Throughout pregnancy and lactation, female rats received the SSRI fluoxetine or vehicle. High resolution 16S ribosomal RNA marker gene sequencing and targeted metabolic analysis were used to assess the fecal microbiome and metabolic availability, respectively.
- Geographic Coverage
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Groningen (Netherlands)
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Access via European Nucleotide Archive (ENA)
Accession #: PRJEB30296 (ERP112729) - Access Restrictions
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Unrestricted access
- Access Instructions
- The sequencing dataset supporting the conclusions of this article is freely available in the European Nucleotide Archive. Other downloadable data is within the article.
- Associated Publications
- Data Type
- Software Used
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Kyoto Encyclopedia of Genes and Genomes (KEGG)Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt)Random Forests implemented in R version 3.4.1
- Study Type
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Empirical Research
- Dataset Format(s)
- FTP, Galaxy
- Data Collection Instruments
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PSP® Spin Stool DNA KitMiSeqmothur v. 1.39QIIME version 1.9.1ChimeraSlayerRibosomal Database Project (RDP) classifier v 2.2PyNASTFastTreeShannon Diversity IndexUniFrac
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