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UMB Dataset
Biomarkers of Airway Inflammation and Asthma Control in Children with Comorbid Sleep-Disordered Breathing
- Authors
- Valerie E. RogersMary E. BollingerMohan E. TulapurkarShijun Zhu3 more author(s)...
- Description
A bi‐directional relationship exists between asthma and obstructive sleep apnea (OSA) in which presence of one is associated with increased prevalence and severity of the other. This study was undertaken to determine if OSA accounted for differences in airway and systemic inflammation in asthmatic children and if inflammation was associated with asthma control. 27 non-obese children aged 4-12 years...
- Subject
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AsthmaInflammationSleep Wake Disorders
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- Unrestricted access
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UMB Dataset
Circadian rhythms, fatigue and bright light therapy in adolescent cancer survivors
- Authors
- Valerie E. Rogers
- Description
This 2-phase study explored the differences in sleep and circadian activity rhythms between adolescents who were within 5 years of completing treatment for any type of cancer and healthy, age-matched controls; and trialed a morning bright light therapy intervention to gather preliminary evidence of its safety, feasibility and outcomes.
- Subject
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Cancer SurvivorsSleep Wake Disorders
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- Registration required
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UMB Dataset
Comparative Measurement of PLMS Between Polysomnography and Actigraphy in Children with Sickle Cell Disease
- Authors
- Valerie E. RogersPaul R. GallagherCarole L. MarcusKwaku Ohene-Frempong2 more author(s)...
- Description
Periodic limb movements in sleep (PLMS) are associated with sleep fragmentation and sympathetic nervous system activation, which in turn have been linked to cognitive and behavioral deficits in children and cardiovascular morbidity in both adults and children. Emerging evidence indicates that many children with sickle cell disease (SCD) have elevated PLMS. The specific aims of this prospective, repeated-measures,...
- Subject
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Anemia, Sickle CellSleep Wake Disorders
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- Unrestricted access
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UMB Dataset
Sleep, circadian rhythms and fatigue in children with CNS tumors hospitalized for high dose chemotherapy
- Authors
- Valerie E. RogersBelinda Mandrell
- Description
This study tested a sleep promotion intervention (randomized controlled trial) in children with recently diagnosed central nervous system tumors admitted to the hospital for high dose chemotherapy in preparation for autologous stem cell rescue. We hypothesized that disturbed sleep of hospitalized pediatric oncology patients would be reduced by altering the hospital sleep environment. Therefore, a randomized,...
- Subject
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Central Nervous System/CancerSleep Wake Disorders
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- Unrestricted access
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UMB Dataset
Polysomnographic Characteristics of a Referred Sample of Children with Sickle Cell Disease
- Authors
- Valerie E. RogersDaniel S. LewinGlenna B. WinnieJeanne Geiger-Brown
- Description
This was a retrospective medical record review of 55 consecutive children aged 2-18 years with sickle cell disease (SCD) (hemoglobin [Hb] SS and Hb SC genotypes) undergoing polysomnography for evaluation of sleep disordered breathing. Polysomnography values were compared between SCD genotypes, 4 age groups, and adenotonsillectomy status using descriptive and nonparametric statistics. Medical record...
- Subject
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Anemia, Sickle CellSleep Wake Disorders
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- Unrestricted access
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UMB Dataset
Sleep Disturbances in Neurobehaviorally Challenged Children with Sickle Cell Disease
- Authors
- Valerie E. RogersEboni I. Lance
- Description
Children with sickle cell disease (SCD) experience neurodevelopmental decline over time. They also tend to have short duration, poor quality sleep and elevated fatigue levels. This study measured sleep via actigraphy over one week and cognitive and behavioral measures in 19 children and adolescents with SCD. Aged 7-18 years, the majority of participants were referred for neurodevelopmental testing...
- Subject
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Anemia, Sickle CellNeurodevelopmental DisordersSleep Wake Disorders
- Access Rights
- Unrestricted access