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UMB Dataset
Human Disease Ontology Project
- Authors
- Lynn M. Schriml (Principal Investigator)
- Description
Human Disease Ontology (DO) Project release files. The DO project actively collaborates with biomedical and clinical researchers and data repositories to coordinate a standardized classification of human disease. The DO's GitHub repository includes the monthly releases (https://tinyurl.com/DiseaseOntologyReleases), of OWL, OBO, JSON and XML formatted files along with DO subsets (ontology slims) for...
- Subject
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BioinformaticsBiological OntologiesClassification
- Access Rights
- Unrestricted access
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UMB Dataset
Development of a Reproducible Swine Model of Chronic Ischemic Mitral Regurgitation: Lessons Learned
- Authors
- Chetan PasrijaRachael W. QuinnHani AlkhatibDouglas Tran7 more author(s)...
- Description
Thirty-five Yorkshire cross swine underwent percutaneous myocardial infarction with ethanol ablation of the circumflex or obtuse marginal (OM) arteries. Echocardiography was performed at various intervals to assess the development of ischemic mitral regurgitation (IMR) and cardiac function. Swine that developed significant IMR were scheduled for mitral valve operations, which were performed using cardiopulmonary...
- Subject
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Mitral Valve Insufficiency
- Access Rights
- Unrestricted access
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UMB Dataset
Single-Nucleus RNA-Seq Reveals Dysregulation of Striatal Cell Identity Due to Huntington’s Disease Mutations
- Authors
- Sonia MalaiyaMarcia Cortes-GutierrezBrian R. HerbSydney R. Coffey5 more author(s)...
- Description
The involvement of specific medium spiny neuro (MSN) subtype and of other striatal cell types remains poorly understood. To gain insight into cell type-specific disease processes, researchers studied the nuclear transcriptomes of 4524 cells from the striatum of a genetically precise knock-in mouse model of the Huntington's Disease (HD) mutation, HttQ175/1. Three 14-month-old and one 15-month-old male...
- Subject
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Sequence Analysis, RNA
- Timeframe
- 2020
- Access Rights
- Unrestricted access
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UMB Dataset
Staphylococcus aureus strain MRSA1, whole genome shotgun sequencing project
- Alternate Title(s)
- Examination of 388 Staphylococcus aureus Isolates from Intensive Care Unit Patients
- Authors
- Timileyin AdedrianStephanie HitchcockLyndsay M. O’HaraJane M. Michalski6 more author(s)...
- Description
The dataset contains data pertaining to the examination of draft genomes of 388 methicillin-resistant Staphylococcus aureus isolates obtained from intensive care unit patients at three geographically distributed hospitals. The purpose of the study was to determine genomic diversity associated with potential health care worker-associated transmission. Relevant statistics, including linked GenBank and...
- Subject
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Disease Transmission, InfectiousIntensive Care UnitsMethicillin-Resistant Staphylococcus aureusWhole Genome Sequencing
- Access Rights
- Unrestricted access
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UMB Dataset
Relative contributions of various endogenous and exogenous factors to the mosquito microbiota
- Authors
- Haikel N. BogaleMatthew V. CannonKalil KeitaDenka Camara10 more author(s)...
- Description
Researchers used a high-throughput sequencing-based assay to characterize the bacterial composition and diversity of 665 individual field-caught mosquitoes, as well as their species, genotype at an insecticide resistance locus, blood-meal composition, and the eukaryotic parasites and viruses they carry. This data was used to rigorously estimate the individual effect of each parameter on the bacterial...
- Subject
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Pest Control, Biological
- Access Rights
- Unrestricted access
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UMB Dataset
Heroin in Transition Study (HIT)
- Authors
- Daniel CiccaroneGeorge J. UnickJenny K. CohenSarah G. Mars1 more author(s)...
- Description
Dataset comprises hospitalization rates for opioid injection-related skin and soft-tissue infections (O-SSTI) correlated with changes in the price and purity of heroin for the years 1993 through 2010, inclusive. Data is derived from the Healthcare Cost and Utilization Project (HCUP) Nationwide Inpatient Sample (NIS) and the Drug Enforcement Administration (DEA) System to Retrieve Information from...
- Subject
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Substance-Related Disorders