UMB Data Catalog

A project of the Health Sciences and Human Services Library
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Results Found: 6
  • UMB Dataset

    Human Disease Ontology Project

    Authors
    Lynn M. Schriml (Principal Investigator)
    Description

    Human Disease Ontology (DO) Project release files. The DO project actively collaborates with biomedical and clinical researchers and data repositories to coordinate a standardized classification of human disease. The DO's GitHub repository includes the monthly releases (https://tinyurl.com/DiseaseOntologyReleases), of OWL, OBO, JSON and XML formatted files along with DO subsets (ontology slims) for...

    Subject
    Bioinformatics
    Biological Ontologies
    Classification
    Access Rights
    Unrestricted access
  • UMB Dataset

    Development of a Reproducible Swine Model of Chronic Ischemic Mitral Regurgitation: Lessons Learned

    Authors
    Chetan Pasrija
    Rachael W. Quinn
    Hani Alkhatib
    Douglas Tran
    7 more author(s)...
    Description

    Thirty-five Yorkshire cross swine underwent percutaneous myocardial infarction with ethanol ablation of the circumflex or obtuse marginal (OM) arteries. Echocardiography was performed at various intervals to assess the development of ischemic mitral regurgitation (IMR) and cardiac function. Swine that developed significant IMR were scheduled for mitral valve operations, which were performed using cardiopulmonary...

    Subject
    Mitral Valve Insufficiency
    Access Rights
    Unrestricted access
  • UMB Dataset

    Single-Nucleus RNA-Seq Reveals Dysregulation of Striatal Cell Identity Due to Huntington’s Disease Mutations

    Authors
    Sonia Malaiya
    Marcia Cortes-Gutierrez
    Brian R. Herb
    Sydney R. Coffey
    5 more author(s)...
    Description

    The involvement of specific medium spiny neuro (MSN) subtype and of other striatal cell types remains poorly understood. To gain insight into cell type-specific disease processes, researchers studied the nuclear transcriptomes of 4524 cells from the striatum of a genetically precise knock-in mouse model of the Huntington's Disease (HD) mutation, HttQ175/1. Three 14-month-old and one 15-month-old male...

    Subject
    Sequence Analysis, RNA
    Timeframe
    2020
    Access Rights
    Unrestricted access
  • UMB Dataset

    Staphylococcus aureus strain MRSA1, whole genome shotgun sequencing project

    Alternate Title(s)
    Examination of 388 Staphylococcus aureus Isolates from Intensive Care Unit Patients
    Authors
    Timileyin Adedrian
    Stephanie Hitchcock
    Lyndsay M. O’Hara
    Jane M. Michalski
    6 more author(s)...
    Description

    The dataset contains data pertaining to the examination of draft genomes of 388 methicillin-resistant Staphylococcus aureus isolates obtained from intensive care unit patients at three geographically distributed hospitals. The purpose of the study was to determine genomic diversity associated with potential health care worker-associated transmission. Relevant statistics, including linked GenBank and...

    Subject
    Disease Transmission, Infectious
    Intensive Care Units
    Methicillin-Resistant Staphylococcus aureus
    Whole Genome Sequencing
    Access Rights
    Unrestricted access
  • UMB Dataset

    Relative contributions of various endogenous and exogenous factors to the mosquito microbiota

    Authors
    Haikel N. Bogale
    Matthew V. Cannon
    Kalil Keita
    Denka Camara
    10 more author(s)...
    Description

    Researchers used a high-throughput sequencing-based assay to characterize the bacterial composition and diversity of 665 individual field-caught mosquitoes, as well as their species, genotype at an insecticide resistance locus, blood-meal composition, and the eukaryotic parasites and viruses they carry. This data was used to rigorously estimate the individual effect of each parameter on the bacterial...

    Subject
    Pest Control, Biological
    Access Rights
    Unrestricted access
  • UMB Dataset

    Heroin in Transition Study (HIT)

    Authors
    Daniel Ciccarone
    George J. Unick
    Jenny K. Cohen
    Sarah G. Mars
    1 more author(s)...
    Description

    Dataset comprises hospitalization rates for opioid injection-related skin and soft-tissue infections (O-SSTI) correlated with changes in the price and purity of heroin for the years 1993 through 2010, inclusive. Data is derived from the Healthcare Cost and Utilization Project (HCUP) Nationwide Inpatient Sample (NIS) and the Drug Enforcement Administration (DEA) System to Retrieve Information from...

    Subject
    Substance-Related Disorders