UMB Data Catalog

Authors: Lynn M. Schriml (Principal Investigator)
Description: Human Disease Ontology (DO) Project release files. The DO project actively collaborates with biomedical and clinical researchers and data repositories to coordinate a standardized classification of human disease. The DO's GitHub repository includes the monthly releases (https://tinyurl.com/DiseaseOntologyReleases), of OWL, OBO, JSON and XML formatted files along with DO subsets (ontology slims) for the Alliance of Genome Resouces, FlyBase, Mouse Genome Informatics Database, the Immune Epitope Database, DO_Cancer_slim (for cancer variant resources), and zoonotic infectious diseases.The DO SPARQL GitHub directory provides a suite (https://tinyurl.com/DiseaseOntologySrcSparql) of data reporting and QC queries for the community to explore DO's data. File formats include OWL, OBO, JSON, and XML. User requests for disease term review or inclusion of new disease terms may be submitted via the DO GitHub tracker: https://github.com/DiseaseOntology/HumanDiseaseOntology/issues.
Subject: Bioinformatics

Biological Ontologies

Classification
Access Rights: Unrestricted access

Authors: Chetan Pasrija

Rachael W. Quinn

Hani Alkhatib

Douglas Tran

7 more author(s)...
Description: Thirty-five Yorkshire cross swine underwent percutaneous myocardial infarction with ethanol ablation of the circumflex or obtuse marginal (OM) arteries. Echocardiography was performed at various intervals to assess the development of ischemic mitral regurgitation (IMR) and cardiac function. Swine that developed significant IMR were scheduled for mitral valve operations, which were performed using cardiopulmonary bypass. Echocardiographic analysis was conducted to evaluate parameters such as ejection fraction, mitral regurgitation severity, and wall motion.
Subject: Mitral Valve Insufficiency
Access Rights: Unrestricted access

Authors: Sonia Malaiya

Marcia Cortes-Gutierrez

Brian R. Herb

Sydney R. Coffey

5 more author(s)...
Description: The involvement of specific medium spiny neuro (MSN) subtype and of other striatal cell types remains poorly understood. To gain insight into cell type-specific disease processes, researchers studied the nuclear transcriptomes of 4524 cells from the striatum of a genetically precise knock-in mouse model of the Huntington's Disease (HD) mutation, HttQ175/1. Three 14-month-old and one 15-month-old male mice were used to generate the primary dataset.
Subject: Sequence Analysis, RNA
Geographic Coverage: Ethiopia
Timeframe: 2020
Access Rights: Unrestricted access

Alternate Title(s): Examination of 388 Staphylococcus aureus Isolates from Intensive Care Unit Patients
Authors: Timileyin Adedrian

Stephanie Hitchcock

Lyndsay M. O’Hara

Jane M. Michalski

6 more author(s)...
Description: The dataset contains data pertaining to the examination of draft genomes of 388 methicillin-resistant Staphylococcus aureus isolates obtained from intensive care unit patients at three geographically distributed hospitals. The purpose of the study was to determine genomic diversity associated with potential health care worker-associated transmission. Relevant statistics, including linked GenBank and SRA accession numbers for each genome assembly, are included in Table 1 of the associated publication.
Subject: Disease Transmission, Infectious

Intensive Care Units

Methicillin-Resistant Staphylococcus aureus

Whole Genome Sequencing
Geographic Coverage: California

Maryland

New York (State)
Access Rights: Unrestricted access

Authors: Haikel N. Bogale

Matthew V. Cannon

Kalil Keita

Denka Camara

10 more author(s)...
Description: Researchers used a high-throughput sequencing-based assay to characterize the bacterial composition and diversity of 665 individual field-caught mosquitoes, as well as their species, genotype at an insecticide resistance locus, blood-meal composition, and the eukaryotic parasites and viruses they carry. This data was used to rigorously estimate the individual effect of each parameter on the bacterial diversity as well as the relative contribution of each parameter to the microbial composition.
Subject: Pest Control, Biological
Access Rights: Unrestricted access

Authors: Daniel Ciccarone

George J. Unick

Jenny K. Cohen

Sarah G. Mars

1 more author(s)...
Description: Dataset comprises hospitalization rates for opioid injection-related skin and soft-tissue infections (O-SSTI) correlated with changes in the price and purity of heroin for the years 1993 through 2010, inclusive. Data is derived from the Healthcare Cost and Utilization Project (HCUP) Nationwide Inpatient Sample (NIS) and the Drug Enforcement Administration (DEA) System to Retrieve Information from Drug Evidence (STRIDE) databases for 27 Metropolitan Statistical Areas (MSAs).
Subject: Substance-Related Disorders
Geographic Coverage: United States