Description: Thirty-five Yorkshire cross swine underwent percutaneous myocardial infarction with ethanol ablation of the circumflex or obtuse marginal (OM) arteries. Echocardiography was performed at various intervals to assess the development of ischemic mitral regurgitation (IMR) and cardiac function. Swine that developed significant IMR were scheduled for mitral valve operations, which were performed using cardiopulmonary bypass. Echocardiographic analysis was conducted to evaluate parameters such as ejection fraction, mitral regurgitation severity, and wall motion.

Subject of Study

Subject Domain

Keywords

Access via Supplementary materials
images, datatables
Access Restrictions: Unrestricted access
Access Instructions: All data is within the article and supplementary materials.
Associated Publications: Pasrija C, Quinn RW, Alkhatib H, Tran D, Bernstein D, Rice M, Kotloff E, Morales D, D'Ambra MN, Vesely MR, Gammie JS. Development of a Reproducible Swine Model of Chronic Ischemic Mitral Regurgitation: Lessons Learned. Ann Thorac Surg. 2021 Jan;111(1):117-125.
Data Type: Clinical Measures

Imaging
Equipment Used: Cook Medical micropuncture sheath
Thin catheter sheath for precise access to small vessels during catheterization.

GE OEC 9800 Plus machine
Fluoroscopy machine providing real-time X-ray imaging during interventional procedures.

Philips iE33 ultrasound system
High-end ultrasound equipment used for detailed imaging and Doppler analysis.

Philips X5 probe
Ultrasound probe designed for general imaging and Doppler studies.

Philips X7-2t probe
Transesophageal echocardiography probe for detailed cardiac imaging from the esophagus.

Pressure Products SafeSheath
Vascular sheath used for safe and controlled insertion of catheters during procedures.
Study Type: Interventional
Dataset Format(s): Microsoft Word, jpg
Data Collection Instruments: Kruskal-Wallis test

Fisher's exact test
Dataset Size: 2MB

UMB Data Catalog

Development of a Reproducible Swine Model of Chronic Ischemic Mitral Regurgitation: Lessons Learned
UMB Dataset