UMB Data Catalog

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UMB Dataset

Development of a Reproducible Swine Model of Chronic Ischemic Mitral Regurgitation: Lessons Learned

UID: 218
Author(s): Chetan Pasrija*, Rachael W. Quinn, Hani Alkhatib, Douglas Tran, Daniel Bernstein...
* Corresponding Author
Description
Thirty-five Yorkshire cross swine underwent percutaneous myocardial infarction with ethanol ablation of the circumflex or obtuse marginal (OM) arteries. Echocardiography was performed at various intervals to assess the development of ischemic mitral regurgitation (IMR) and cardiac function. Swine that developed significant IMR were scheduled for mitral valve operations, which were performed using cardiopulmonary bypass. Echocardiographic analysis was conducted to evaluate parameters such as ejection fraction, mitral regurgitation severity, and wall motion.
Subject of Study
Yorkshire
Subject Domain
Mitral Valve Insufficiency
Keywords
Disease Models, Animal
Myocardial Infarction

Access

Restrictions
Unrestricted access
Instructions
All data is within the article and supplementary materials.
Associated Publications
Pasrija C, Quinn RW, Alkhatib H, Tran D, Bernstein D, Rice M, Kotloff E, Morales D, D'Ambra MN, Vesely MR, Gammie JS. Development of a Reproducible Swine Model of Chronic Ischemic Mitral Regurgitation: Lessons Learned. Ann Thorac Surg. 2021 Jan;111(1):117-125.
Data Type
Clinical Measures
Imaging
Equipment Used
Cook Medical micropuncture sheath

Thin catheter sheath for precise access to small vessels during catheterization.

GE OEC 9800 Plus machine

Fluoroscopy machine providing real-time X-ray imaging during interventional procedures.

Philips iE33 ultrasound system

High-end ultrasound equipment used for detailed imaging and Doppler analysis.

Philips X5 probe

Ultrasound probe designed for general imaging and Doppler studies.

Philips X7-2t probe

Transesophageal echocardiography probe for detailed cardiac imaging from the esophagus.

Pressure Products SafeSheath

Vascular sheath used for safe and controlled insertion of catheters during procedures.

Study Type
Interventional
Dataset Format(s)
Microsoft Word, jpg
Data Collection Instruments
Kruskal-Wallis test
Fisher's exact test
Dataset Size
2MB