UMB Data Catalog

Authors: Valerie E. Rogers

Mary E. Bollinger

Mohan E. Tulapurkar

Shijun Zhu

3 more author(s)...
Description: A bi‐directional relationship exists between asthma and obstructive sleep apnea (OSA) in which presence of one is associated with increased prevalence and severity of the other. This study was undertaken to determine if OSA accounted for differences in airway and systemic inflammation in asthmatic children and if inflammation was associated with asthma control. 27 non-obese children aged 4-12 years with persistent asthma, with or without OSA, were recruited for the research. Asthma control was measured with the Childhood Asthma Control Test. Participants underwent polysomnography and blood sampling, and those with OSA also underwent clinically indicated adenotonsillectomy. Tonsils and sera were analyzed for 11 cytokines. The dataset includes demographic data, health history, spirometry/polysomnographic measures, and immunoassay values.
Subject: Asthma

Inflammation

Sleep Wake Disorders
Access Rights: Unrestricted access

Authors: Valerie E. Rogers

Daniel S. Lewin

Glenna B. Winnie

Jeanne Geiger-Brown
Description: This was a retrospective medical record review of 55 consecutive children aged 2-18 years with sickle cell disease (SCD) (hemoglobin [Hb] SS and Hb SC genotypes) undergoing polysomnography for evaluation of sleep disordered breathing. Polysomnography values were compared between SCD genotypes, 4 age groups, and adenotonsillectomy status using descriptive and nonparametric statistics. Medical record data were collected for 12 months pre-polysomnography and 12 months post-polysomnography/adenotonsillectomy. This dataset includes demographic data, SCD type, polysomnographic values, and clinical measures.
Subject: Anemia, Sickle Cell

Sleep Wake Disorders
Access Rights: Unrestricted access

Authors: Valerie E. Rogers
Description: This 2-phase study explored the differences in sleep and circadian activity rhythms between adolescents who were within 5 years of completing treatment for any type of cancer and healthy, age-matched controls; and trialed a morning bright light therapy intervention to gather preliminary evidence of its safety, feasibility and outcomes.
Subject: Cancer Survivors

Sleep Wake Disorders
Geographic Coverage: United States
Access Rights: Registration required

Authors: Valerie E. Rogers

Belinda Mandrell
Description: This study tested a sleep promotion intervention (randomized controlled trial) in children with recently diagnosed central nervous system tumors admitted to the hospital for high dose chemotherapy in preparation for autologous stem cell rescue. We hypothesized that disturbed sleep of hospitalized pediatric oncology patients would be reduced by altering the hospital sleep environment. Therefore, a randomized, attention-controlled sleep intervention was implemented in children and adolescents with central nervous system tumors admitted for 6 days for high dose chemotherapy prior to stem cell transplant. Children and adolescents diagnosed with medulloblastoma or histologically similar tumor, 4 to 19 years and their parent were recruited over 3 years.Questionnaires used to gather the data were: Fatigue Scale-Child, Fatigue Scale-Adolescent, Fatigue Scale-Parent. Data was also obtained using actigraphy.
Subject: Central Nervous System/Cancer

Sleep Wake Disorders
Geographic Coverage: United States
Access Rights: Unrestricted access

Authors: Valerie E. Rogers

Belinda Mandrell
Description: This study measured circadian activity rhythms (CAR) and fatigue in children and adolescents with acute lymphoblastic leukemia on maintenance chemotherapy during the 5 days prior to a pulse of dexamethasone and the 5 days after the start of dexamethasone. CAR was measured via an actigraph worn continuously for 10 days. Fatigue was measured at 4 time points. The fatigue measures used for this study were Fatigue Scale-Child, Fatigue Scale-Adolescent and Fatigue Scale-Parent. The aims of this descriptive study were to compare CAR during the periods before and during dexamethasone therapy, and to explore the hypothesis that less robust CAR was associated with greater fatigue.
Subject: Circadian Rhythm

Dexamethasone

Leukemia
Geographic Coverage: International

United States
Access Rights: Unrestricted access