UMB Data Catalog

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Results Found: 4
  • UMB Dataset

    Transcriptomic comparisons of macroscopically normal-appearing and scarred lung tissues in idiopathic pulmonary fibrosis

    Authors
    Sergei P. Atamas
    Description

    Idiopathic pulmonary fibrosis (IPF) produces scarring in the peripheral and basilar regions of the lung with macroscopically normal-appearing tissue in the central and apical areas. This study involved comparing transcriptomic profiles of the latter with transcriptomes of scarred IPF and healthy control lung tissues. The primary goal of the research was to elucidate the pathobiology of the disease...

    Subject
    Gene Expression Profiling
    Sequence Analysis
    Access Rights
    Unrestricted access
  • UMB Dataset

    Genomic and Transcriptomic Survey of Mucormycosis-Causing Fungi

    Authors
    Vincent M. Bruno
    Marcus C. Chibucos
    Sean Daugherty
    Joshua Orvis
    7 more author(s)...
    Description

    Mucormycosis is a life-threatening disease especially to individuals who are immunosuppressed or have chronic health conditions. Several genera within the fungal order Mucorales have been identified as causative agents. This dataset is the result of research elucidating the population genetics, phylogeny, and pathogenicity of the infectious fungi. Included are de novo genome sequences and annotations...

    Subject
    Fungi/genetics
    Fungi/pathogenicity
    Access Rights
    Unrestricted access
  • UMB Dataset

    Plasmodium vivax Transcriptomes Reveal Stage-specific Chloroquine Response and Differential Regulation of Male and Female Gametocytes

    Authors
    Adam Kim
    Jean Popovici
    Didier Menard
    David Serre
    Description

    Plasmodium vivax is the most widespread human malaria parasite. However, its biology is little understood for a number of reasons, not the least of which is the inability to continuously propagate it in vitro. Utilizing samples of whole blood taken from 26 Cambodian patients who were determined to be solely infected with the parasite, this research investigated three aspects of P. vivax activity: 1)...

    Subject
    Gene Expression Profiling
    Plasmodium vivax
    Access Rights
    Unrestricted access
  • UMB Dataset

    Cervicovaginal Microbiota and Local Immune Response Modulate the Risk of Spontaneous Preterm Delivery

    Authors
    Jacques Ravel
    Michal A. Elovitz
    Pawel Gajer
    Valerie Ris
    3 more author(s)...
    Description

    This study was undertaken to investigate the correlation between cervicovaginal microbiota, immunological factors, and race and the risk of premature birth. From a cohort of 2000 women with singleton pregnancies, 539 participated in the research with 432 delivering full term and 107 experiencing spontaneous preterm delivery. The racial breakdown consisted of 402 African American, 115 White, and 22...

    Subject
    Premature Birth
    Risk Factors
    Access Rights
    Approval required
    Registration required