UMB Data Catalog

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Results Found: 2
  • UMB Dataset

    MR-Guided Transcranial Focused Ultrasound Safely Enhances Interstitial Disperson of Large Polymeric Nanoparticles in the Living Brain

    Authors
    Graeme F. Woodworth
    Victor Frenkel
    David S. Hersh
    Pavlos Anastasiadis
    7 more author(s)...
    Description

    This study tested the viability of using MRI-guided transcranial focused ultrasound (MRgFUS) to modify the interstitial space in the living brain. As a non-invasive technique, success in generating spatially controlled, non-destructive changes could lead to clinical applications such as enhancing delivery of therapeutics and altering fluid and pressure dynamics. The research involved the use of computer...

    Subject
    Brain
    Magnetic Resonance Imaging, Interventional
    Ultrasonic Therapy
    Access Rights
    Unrestricted access
  • UMB Dataset

    Nanomagnetic-Mediated Drug Delivery for the Treatment of Dental Disease

    Authors
    Radi Masri
    Description

    This research tested the efficacy of utilizing nanoparticles, external magnetic forces, and dentinal tubules as conduits for delivering therapeutic agents to dental pulp. Moderate-size cavities were created in the dentin of rat mandibular molars and treated via the use of external magnetic forces to actively transport prednisolone-eluting magnetic nanoparticles to tooth pulp. Control groups included...

    Subject
    Endodontics