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Results Found: 29
  • UMB Dataset

    FLT3-ITD Allelic Burden and Acute Promyelocytic Leukemia Risk Stratification

    Authors
    Andrew Y. Li
    Sarah M. Kashanian
    Bryan C. Hambley
    Kyle Zacholski
    13 more author(s)...
    Description

    The dataset includes information on patients aged 18 or older treated for acute promyelocytic leukemia (APL) at the University of Maryland Medical Center and Johns Hopkins Hospital between January 2000 and May 2020. It encompasses data on FLT3-ITD mutations, including allelic burden and insertion length estimation. Patient demographics, laboratory results, treatment regimens, and outcomes were recorded....

    Subject
    DNA Mutational Analysis
    Access Rights
    Approval required
  • UMB Dataset

    Hip Abductor and Adductor Rate of Torque Development and Muscle Activation, but Not Muscle Size, Are Associated With Functional Performance

    Authors
    Marcel Bahia Lanza
    Kelly Rock
    Victoria Marchese
    Odessa R. Addison
    1 more author(s)...
    Description

    Twenty healthy young adults aged 18 to 35 years underwent various tests and measurements related to hip abduction and adduction strength, neuromuscular activation, muscle thickness via ultrasound imaging, and physical performance tests such as the Four Square Step Test (FSST) and the two-legged side hop test. Measures included maximal voluntary isometric contractions, surface electromyography (EMG)...

    Subject
    Hip Joint
    Physical Functional Performance
    Access Rights
    Unrestricted access
    Approval required
  • UMB Dataset

    Comparison of angle-to-angle distance and corneal diameter in pediatric eyes using ultrasound biomicroscopy

    Authors
    Taylor D. Kolosky
    Anusha U. Saga
    Donald F. Dariano III
    Urjita Das
    4 more author(s)...
    Description

    54 eyes from 41 pediatric participants aged 0.1 to 11.3 years, including healthy controls and subjects with primary congenital glaucoma, were imaged at the University of Maryland, Baltimore between November 2014 and May 2022. Corneal photographs and ultrasound biomicroscopy (UBM) images were analyzed. Measurements included horizontal and vertical corneal diameters from photographs and angle-to-angle...

    Subject
    Glaucoma / diagnostic imaging
    Access Rights
    Unrestricted access
  • UMB Dataset

    A 2-Year Clinical Evaluation of Fissure Sealants

    Alternate Title(s)
    Evaluation of Resin Based and Glass Ionomer Based Sealants Placed With or Without Tooth Preparation
    Authors
    Vineet Dhar
    Haiyan Chen
    Description

    25 children ranging in age from 6 to 10 years participated in this bilateral split-mouth study evaluating two dental sealants for retention and secondary caries development. Data were collected comparing resin based and glass ionomer based sealants with and without tooth preparation at 6-month intervals over a 2 year period. Dataset includes demographic and clinical measures and sealant performance...

    Subject
    Dental Materials
    Access Rights
    Registration required
  • UMB Dataset

    Serious adverse events of special interest following mRNA COVID-19 vaccination in randomized trials in adults

    Authors
    Joseph Fraiman
    Juan Erviti
    Mark Jones
    Sander Greenland
    3 more author(s)...
    Description

    An adapted version of the Brighton Collaboration priority list was used to evaluate serious adverse events (SAE) of special interest observed in mRNA Covid-19 vaccine trials. In December of 2020, reviewers searched journal publications and trial data on the FDA’s and Health Canada’s websites to locate SAE results tables for these trials. For each trial, blinded SAE tables were prepared. Using these...

    Subject
    COVID-19/prevention & control
    Vaccines
    Timeframe
    2020
    Access Rights
    Unrestricted access
  • UMB Dataset

    Biomarkers of lesion severity in a rodent model of nonarthritic anterior ischemic optic neuropathy (rNAION)

    Authors
    Yan Guo
    Zara Mehrabian
    Mary A. Johnson
    Neil R. Miller
    3 more author(s)...
    Description

    The rodent model of nonarthritic anterior ischemic optic neuropathy (rNAION) is similar in many of its pathophysiological responses to clinical NAION. Like human NAION, there is significant variability in the severity of the lesion produced, and little is known of the parameters associated with rNAION induction severity or if pre- or early post-induction biomarkers can be identified that enable prediction...

    Subject
    Optic Nerve Diseases
    Access Rights
    Unrestricted access
  • UMB Dataset

    Dataset for Vaginal Human Papilomavirus Infection Among Adolescent and Early Adult Girls in Jos, Nigeria

    Authors
    Nanma T. Cosmas
    Lohya Nimzing
    Daniel Z. Egah
    Oluranti A. Famooto
    2 more author(s)...
    Description

    "Data from 205 adolescent and early adult girls in Jos, Nigeria was collected to assess risk factors for vaginal human papillomavirus (HPV) infection, knowledge about HPV vaccines, and assess willingness to receive the HPV vaccine. Data on prevalence and patterns of HPV infections was also collected. Participants, age 9 to 20 years old, were recruited from 10 randomly selected schools. Research...

    Subject
    Human Papillomavirus Viruses
    Access Rights
    Unrestricted access
  • UMB Dataset

    Development of a Reproducible Swine Model of Chronic Ischemic Mitral Regurgitation: Lessons Learned

    Authors
    Chetan Pasrija
    Rachael W. Quinn
    Hani Alkhatib
    Douglas Tran
    7 more author(s)...
    Description

    Thirty-five Yorkshire cross swine underwent percutaneous myocardial infarction with ethanol ablation of the circumflex or obtuse marginal (OM) arteries. Echocardiography was performed at various intervals to assess the development of ischemic mitral regurgitation (IMR) and cardiac function. Swine that developed significant IMR were scheduled for mitral valve operations, which were performed using cardiopulmonary...

    Subject
    Mitral Valve Insufficiency
    Access Rights
    Unrestricted access
  • UMB Dataset

    Immunologic Response to ART by Age Among Treatment-Naive Patients in Sub-Saharan Africa

    Alternate Title(s)
    Immunologic Response to Antiretroviral Therapy by Age Among Treatment-Naive Patients in Sub-Saharan Africa
    Authors
    Kristen A. Stafford
    Laurence S. Magder
    Laura L. Hungerford
    Jack M. Guralnik
    3 more author(s)...
    Description

    This study investigated the association of age with CD4+ cell counts of HIV patients receiving antiretroviral treatment (ART) over a 4 year period. Data were collected from 126,672 previously treatment-naïve patients in 4 Sub-Saharan African nations. The baseline CD4+ count was measured at onset of ART and at 6-month intervals thereafter. The predictor variable was the age at initiation of therapy...

    Subject
    HIV Infections
  • UMB Dataset

    Factors Associated with Outcomes of Pre-ART HIV Care

    Alternate Title(s)
    Factors Associated with Outcomes of Pre-Antiretroviral HIV Care
    Authors
    Kristen A. Stafford
    Lucy W. Nganga
    Tuhuma Tulli
    Karen G. Fleischman Foreit
    Description

    In 2015 the World Health Organization (WHO) eliminated CD4 restrictions for initiating antiretroviral therapy (ART) for people living with HIV (PLHIV) in developing countries. However, the success of therapy is also dependent upon additional health and demographic characteristics of HIV patients at the time they enroll in care. This study investigated pre-ART (time between enrollment and initiation...

    Subject
    HIV Infections