UMB Data Catalog

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Results Found: 34
  • UMB Dataset

    A 2-Year Clinical Evaluation of Fissure Sealants

    Alternate Title(s)
    Evaluation of Resin Based and Glass Ionomer Based Sealants Placed With or Without Tooth Preparation
    Authors
    Vineet Dhar
    Haiyan Chen
    Description

    25 children ranging in age from 6 to 10 years participated in this bilateral split-mouth study evaluating two dental sealants for retention and secondary caries development. Data were collected comparing resin based and glass ionomer based sealants with and without tooth preparation at 6-month intervals over a 2 year period. Dataset includes demographic and clinical measures and sealant performance...

    Subject
    Dental Materials
    Access Rights
    Registration required
  • UMB Dataset

    Serious adverse events of special interest following mRNA COVID-19 vaccination in randomized trials in adults

    Authors
    Joseph Fraiman
    Juan Erviti
    Mark Jones
    Sander Greenland
    3 more author(s)...
    Description

    An adapted version of the Brighton Collaboration priority list was used to evaluate serious adverse events (SAE) of special interest observed in mRNA Covid-19 vaccine trials. In December of 2020, reviewers searched journal publications and trial data on the FDA’s and Health Canada’s websites to locate SAE results tables for these trials. For each trial, blinded SAE tables were prepared. Using these...

    Subject
    COVID-19/prevention & control
    Vaccines
    Timeframe
    2020
    Access Rights
    Unrestricted access
  • UMB Dataset

    FLT3-ITD Allelic Burden and Acute Promyelocytic Leukemia Risk Stratification

    Authors
    Andrew Y. Li
    Sarah M. Kashanian
    Bryan C. Hambley
    Kyle Zacholski
    13 more author(s)...
    Description

    The dataset includes information on patients aged 18 or older treated for acute promyelocytic leukemia (APL) at the University of Maryland Medical Center and Johns Hopkins Hospital between January 2000 and May 2020. It encompasses data on FLT3-ITD mutations, including allelic burden and insertion length estimation. Patient demographics, laboratory results, treatment regimens, and outcomes were recorded....

    Subject
    DNA Mutational Analysis
    Access Rights
    Approval required
  • UMB Dataset

    Hip Abductor and Adductor Rate of Torque Development and Muscle Activation, but Not Muscle Size, Are Associated With Functional Performance

    Authors
    Marcel Bahia Lanza
    Kelly Rock
    Victoria Marchese
    Odessa R. Addison
    1 more author(s)...
    Description

    Twenty healthy young adults aged 18 to 35 years underwent various tests and measurements related to hip abduction and adduction strength, neuromuscular activation, muscle thickness via ultrasound imaging, and physical performance tests such as the Four Square Step Test (FSST) and the two-legged side hop test. Measures included maximal voluntary isometric contractions, surface electromyography (EMG)...

    Subject
    Hip Joint
    Physical Functional Performance
    Access Rights
    Unrestricted access
    Approval required
  • UMB Dataset

    Comparison of angle-to-angle distance and corneal diameter in pediatric eyes using ultrasound biomicroscopy

    Authors
    Taylor D. Kolosky
    Anusha U. Saga
    Donald F. Dariano III
    Urjita Das
    4 more author(s)...
    Description

    54 eyes from 41 pediatric participants aged 0.1 to 11.3 years, including healthy controls and subjects with primary congenital glaucoma, were imaged at the University of Maryland, Baltimore between November 2014 and May 2022. Corneal photographs and ultrasound biomicroscopy (UBM) images were analyzed. Measurements included horizontal and vertical corneal diameters from photographs and angle-to-angle...

    Subject
    Glaucoma / diagnostic imaging
    Access Rights
    Unrestricted access
  • UMB Dataset

    Factors Associated with Outcomes of Pre-ART HIV Care

    Alternate Title(s)
    Factors Associated with Outcomes of Pre-Antiretroviral HIV Care
    Authors
    Kristen A. Stafford
    Lucy W. Nganga
    Tuhuma Tulli
    Karen G. Fleischman Foreit
    Description

    In 2015 the World Health Organization (WHO) eliminated CD4 restrictions for initiating antiretroviral therapy (ART) for people living with HIV (PLHIV) in developing countries. However, the success of therapy is also dependent upon additional health and demographic characteristics of HIV patients at the time they enroll in care. This study investigated pre-ART (time between enrollment and initiation...

    Subject
    HIV Infections
  • UMB Dataset

    Immunologic Response to ART by Age Among Treatment-Naive Patients in Sub-Saharan Africa

    Alternate Title(s)
    Immunologic Response to Antiretroviral Therapy by Age Among Treatment-Naive Patients in Sub-Saharan Africa
    Authors
    Kristen A. Stafford
    Laurence S. Magder
    Laura L. Hungerford
    Jack M. Guralnik
    3 more author(s)...
    Description

    This study investigated the association of age with CD4+ cell counts of HIV patients receiving antiretroviral treatment (ART) over a 4 year period. Data were collected from 126,672 previously treatment-naïve patients in 4 Sub-Saharan African nations. The baseline CD4+ count was measured at onset of ART and at 6-month intervals thereafter. The predictor variable was the age at initiation of therapy...

    Subject
    HIV Infections
  • UMB Dataset

    Amish Complex Genetic Disease Database

    Description

    The Amish Research Group of the University of Maryland School of Medicine has been studying the Old Order Amish population in Lancaster County, PA, since 1993. This database currently consists of health-related data on over 7,000 adults resulting from studies ranging from population and basic science to clinical and translational research. Areas of investigation include: Cardiovascular Risk, Diabetes,...

    Subject
    Amish
    Ethnic Groups/genetics
    Genetics, Population
    Health Status Indicators
    Access Rights
    Approval required
    Local Experts
    Alan R. Shuldiner
    Braxton C. Mitchell

  • Orofacial Pain: Prospective Evaluation and Risk Assessment (OPPERA)

    Alternate Title(s)
    OPPERA
    Description

    This dataset is the result of a multi-center, 7 year prospective investigation into the biopsychosocial, environmental, and genetic risk factors associated with the onset and persistence of temporomandibular disorders (TMD). The OPPERA project consisted of 4 observational studies: a prospective cohort study of first-onset TMD, a baseline case-control study of chronic TMD, a matched case-control study...

    Subject
    Craniomandibular Disorders
    Facial Pain
    Risk Factors
    Access Rights
    Approval required
    Registration required
    Local Experts
    Joel D. Greenspan
    Meg Johantgen
    Shijun Zhu
    Susan G. Dorsey
  • UMB Dataset

    Comparative Measurement of PLMS Between Polysomnography and Actigraphy in Children with Sickle Cell Disease

    Authors
    Valerie E. Rogers
    Paul R. Gallagher
    Carole L. Marcus
    Kwaku Ohene-Frempong
    2 more author(s)...
    Description

    Periodic limb movements in sleep (PLMS) are associated with sleep fragmentation and sympathetic nervous system activation, which in turn have been linked to cognitive and behavioral deficits in children and cardiovascular morbidity in both adults and children. Emerging evidence indicates that many children with sickle cell disease (SCD) have elevated PLMS. The specific aims of this prospective, repeated-measures,...

    Subject
    Anemia, Sickle Cell
    Sleep Wake Disorders
    Access Rights
    Unrestricted access