UMB Data Catalog

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Results Found: 213
  • UMB Dataset

    #Coronavirus on TikTok: user engagement with misinformation as a potential threat to public health behavior

    Authors
    Jonathan D. Baghdadi
    K.C. Coffey
    Rachael Belcher
    James Frisbie
    3 more author(s)...
    Description

    A sample of TikTok videos associated with the hashtag #coronavirus were downloaded on September 20, 2020. Misinformation was evaluated on a scale (low, medium, high) using a codebook developed by experts in infectious diseases. Multivariable modeling was used to evaluate factors associated with number of views and presence of user comments indicating intention to change behavior. Videos and related...

    Subject
    Communication
    Access Rights
    Unrestricted access
  • UMB Dataset

    60 Years after Kefauver: Household income required to buy prescription drugs in the United States and abroad

    Authors
    T. Joseph Mattingly II
    Dominique Seo
    Adam M. Ostrovsky
    David J. Vanness
    1 more author(s)...
    Description

    Using the framework of the historical analysis presented to the Senate Subcommittee on Antitrust and Monopoly, drug prices relative to income in the United States are compared to other Organization for Economic Co-Operation and Development (OECD) countries to improve treatment access and affordability. Countries were selected based on drug price and income data availability and inclusion in the...

    Subject
    Health Care Costs
    Timeframe
    2018
    Access Rights
    Unrestricted access
  • UMB Dataset

    A 2-Year Clinical Evaluation of Fissure Sealants

    Alternate Title(s)
    Evaluation of Resin Based and Glass Ionomer Based Sealants Placed With or Without Tooth Preparation
    Authors
    Vineet Dhar
    Haiyan Chen
    Description

    25 children ranging in age from 6 to 10 years participated in this bilateral split-mouth study evaluating two dental sealants for retention and secondary caries development. Data were collected comparing resin based and glass ionomer based sealants with and without tooth preparation at 6-month intervals over a 2 year period. Dataset includes demographic and clinical measures and sealant performance...

    Subject
    Dental Materials
    Access Rights
    Registration required
  • UMB Dataset

    A Survey of Pharmacogenomics Testing Among Physicians, Pharmacists, and Researchers From China

    Authors
    Chengxian Guo
    Biwen Hu
    Chengjun Guo
    Xiangguang Meng
    7 more author(s)...
    Description

    A 20 question survey was administered to 422 participants to gather data on factors influencing pharmacogenomics (PGx). The surveying period was from April to May 2019. Participants included physicians, pharmacists, and researchers. The survey link online was conducted via WeChat. Data collection from the surveys was conducted via popular professional survey platform "Wenjuanxing."

    Subject
    Pharmacology, Clinical
    Timeframe
    2019
    Access Rights
    Unrestricted access
  • ACGME Case Log Graduate Statistic National Report: Ophthalmology

    Description

    The Accreditation Council for Graduate Medical Education (ACGME) sets standards for US graduate medical education (residency and fellowship) programs and the institutions that sponsor them, and renders accreditation decisions based on compliance with these standards. Residents and fellows provide regular feedback to the ACGME about their programs, offering an inside view that helps the organization...

    Subject
    Internship and Residency
    Ophthalmology/education
    Access Rights
    Unrestricted access
  • UMB Dataset

    Adjuvant-containing control arms in pivotal quadrivalent human papillomavirus vaccine trials: restoration of previously unpublished methodology

    Authors
    Peter Doshi
    Florence Bourgeois
    Kyungwan Hong
    Mark Jones
    4 more author(s)...
    Description

    Randomised, placebo-controlled clinical trials are considered the gold standard for evaluating new vaccines. To assess its efficacy and safety, the manufacturer of quadrivalent human papillomavirus (qHPV) vaccine conducted multiple clinical trials involving approximately 30,000 volunteers. The trials of the qHPV vaccine are reported as ‘placebo-controlled.’ However, participants in the ‘placebo’ arms...

    Subject
    Clinical Trials as Topic/ethics
    Clinical Trials as Topic/standards
    Access Rights
    Unrestricted access
    Approval required
  • UMB Dataset

    Amish Complex Genetic Disease Database

    Description

    The Amish Research Group of the University of Maryland School of Medicine has been studying the Old Order Amish population in Lancaster County, PA, since 1993. This database currently consists of health-related data on over 7,000 adults resulting from studies ranging from population and basic science to clinical and translational research. Areas of investigation include: Cardiovascular Risk, Diabetes,...

    Subject
    Amish
    Ethnic Groups/genetics
    Genetics, Population
    Health Status Indicators
    Access Rights
    Approval required
    Local Experts
    Alan R. Shuldiner
    Braxton C. Mitchell
  • UMB Dataset

    An optimized protocol for single nuclei isolation from clinical biopsies for RNA-seq

    Authors
    Thomas V. Rousselle
    Jennifer M. McDaniels
    Amol C. Shetty
    Elissa Bardhi
    2 more author(s)...
    Description

    Researchers present an optimized protocol for single nuclei RNA sequencing (snRNA-seq) that is fast, low, cost, and time effective due to the elimination of cell sorting and ultra-centrifugation. Both human and mouse tissue biopsies were assessed. Human kidney graft biopsies were collected from five kidney transplant recipients. Mouse needle biopsies were collected from heart, liver, kidney, spleen,...

    Subject
    High-Throughput Nucleotide Sequencing
    Access Rights
    Unrestricted access
  • UMB Dataset

    Analysis of Rickettsia typhi-Infected and Uninfected Cat Flea (Ctenocephalides felis) Midgut cDNA Libraries: Deciphering Molecular Pathways Involved in Host Response to R. typhi Infection

    Authors
    Abdu F. Azad
    Sheila M. Dreher-Lesnick
    Shane M. Ceraul
    Sky C. Lesnick
    4 more author(s)...
    Description

    Murine typhus is a febrile disease caused by the bacterium, Rickettsia typhi (R. typhi), and transmitted via infected fleas. This study investigated midgut responses of infected versus uninfected cat fleas (Ctenocephalides felis) by constructing cDNA libraries and examining transcript levels. Select C. felis serine proteases, GTPases and defense response genes were compared to identify differences...

    Subject
    Ctenocephalides
    Gene Expression Profiling
    Rickettsia typhi
    Transcription, Genetic
    Timeframe
    2009
    Access Rights
    Unrestricted access
  • UMB Dataset

    Antidepressant treatment with fluoxetine during pregnancy and lactation modulates the gut microbiome and metabolome in a rat model relevant to depression

    Authors
    Anouschka S. Ramsteijn
    Eldin Jašarević
    Danielle J. Houwing
    Tracy L. Bale
    1 more author(s)...
    Description

    Data and figures are provided on the effects of fluoxetine, a selective serotin reuptake inhibitor (SSRI) antidepressant, on the gut microbiome and metabolome in a rat model to better understand the effect of this drug on women during gestation and lactation. Throughout pregnancy and lactation, female rats received the SSRI fluoxetine or vehicle. High resolution 16S ribosomal RNA marker gene sequencing...

    Subject
    Antidepressive Agents
    Lactation
    Pregnancy
    Access Rights
    Unrestricted access