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Development of a Reproducible Swine Model of Chronic Ischemic Mitral Regurgitation: Lessons Learned
UMB Dataset- Authors
- Chetan PasrijaRachael W. QuinnHani AlkhatibDouglas Tran7 more author(s)...
- Description
Thirty-five Yorkshire cross swine underwent percutaneous myocardial infarction with ethanol ablation of the circumflex or obtuse marginal (OM) arteries. Echocardiography was performed at various intervals to assess the development of ischemic mitral regurgitation (IMR) and cardiac function. Swine that developed significant IMR were scheduled for mitral valve operations, which were performed using cardiopulmonary bypass. Echocardiographic analysis was conducted to evaluate parameters such as ejection fraction, mitral regurgitation severity, and wall motion.
- Subject
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Mitral Valve Insufficiency
- Access Rights
- Unrestricted access