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  • UMB Dataset

    Approaches to Potentiated Neuroprotective Treatment in the Rodent Model of Ischemic Optic Neuropathy

    Authors
    Zara Mehrabian
    Yan Guo
    Neil R. Miller
    Amanda D. Henderson
    2 more author(s)...
    Description

    Nonarthritic anterior ischemic optic neuropathy (NAION) commonly causes sudden optic nerve (ON)-related vision loss. The rodent NAION model (rAION) closely resembles NAION in presentation and physiological responses. Researchers hypothesized that blocking pro-inflammatory prostaglandin (PGE2) production by inhibiting monoacylglycerol lipase or cyclooxygenase activity and co-administering PGJ2 would...

    Subject
    Optic Nerve Diseases
    Timeframe
    2021
    Access Rights
    Unrestricted access