UMB Data Catalog
A project of the Health Sciences and Human Services Library-
Culture Condition of Bone Marrow Stromal Cells Affects Quantity and Quality of the Extracellular Vesicles
UMB Dataset- Authors
- Amanda L. ScheiberCierra A. ClarkTakashi KaitoMasahiro Iwamoto3 more author(s)...
- Description
Extracellular vehicles (EVs) released from bone marrow stromal cells (BMSCs) have been demonstrated to play an important role in their therapeutic actions for various diseases. This study establishes a scalable and reproducible EV manufacturing processes needed to develop successful implementation of EV therapy for patients. Using human BMSCs isolated from nine healthy donors, researchers examined the effects of high-performance culture media that can rapidly expand BMSCs on EV production and quality in comparison with the conventional culture medium.
- Subject
-
Cell- and Tissue-Based Therapy/methods
- Access Rights
- Unrestricted access