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  • UMB Dataset

    MR-Guided Transcranial Focused Ultrasound Safely Enhances Interstitial Disperson of Large Polymeric Nanoparticles in the Living Brain

    Authors
    Graeme F. Woodworth
    Victor Frenkel
    David S. Hersh
    Pavlos Anastasiadis
    7 more author(s)...
    Description

    This study tested the viability of using MRI-guided transcranial focused ultrasound (MRgFUS) to modify the interstitial space in the living brain. As a non-invasive technique, success in generating spatially controlled, non-destructive changes could lead to clinical applications such as enhancing delivery of therapeutics and altering fluid and pressure dynamics. The research involved the use of computer...

    Subject
    Brain
    Magnetic Resonance Imaging, Interventional
    Ultrasonic Therapy
    Access Rights
    Unrestricted access