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  • UMB Dataset

    Refinement of a Live Attenuated Salmonella enterica Serovat Newport Vaccine with Improved Safety

    Description

    Non-typhoidal Salmonella (NTS) is responsible for approximately 93 million cases of gastroenteritis annually. Little research has been directed towards a development of vaccines against Salmonella serogroups O:6,7 or O:8. Researchers constructed a live attenuated serogroup O:8 vaccine, CVS 1979, by deleting guaBA, htrA, and aroA from the genome of S. Newport. Over the course of 6 weeks, 6 to 8-week-old...

    Subject
    Salmonella Vaccines
    Vaccine Development
    Access Rights
    Unrestricted access