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- Bioinformatics 1
- Biological Ontologies 1
- COVID-19 1
- Classification 1
- Clinical Trials as Topic/ethics 1
- Clinical Trials as Topic/standards 1
- Colitis, Ulcerative/drug therapy 1
- Computers, Handheld 1
- Crohn Disease/drug therapy 1
- Drug-Related Side Effects and Adverse Reactions 1
- Global Burden of Disease 1
- Global Health/statistics & numerical data 1
- Paramyxoviridae Infections 1
- Respiratory Tract Infections 1
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UMB Dataset
Human Disease Ontology Project
- Authors
- Lynn M. Schriml (Principal Investigator)
- Description
Human Disease Ontology (DO) Project release files. The DO project actively collaborates with biomedical and clinical researchers and data repositories to coordinate a standardized classification of human disease. The DO's GitHub repository includes the monthly releases (https://tinyurl.com/DiseaseOntologyReleases), of OWL, OBO, JSON and XML formatted files along with DO subsets (ontology slims) for...
- Subject
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BioinformaticsBiological OntologiesClassification
- Access Rights
- Unrestricted access
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UMB Dataset
Global burden of acute lower respiratory infection associated with human parainfluenza virus in children under five years for 2018: a systematic review and meta-analysis
- Authors
- Respiratory Virus Global Epidemiology NetworkXin WangHarish Nair
- Description
Through a systematic review, this study collected published and unpublished data on human parainfluenza virus (hPIV) burden to estimate the global and regional number of hPIV-associated acute lower respiratory infections (ALRI) cases, hospitalizations, and mortality by children under five years (stratified 0–5 months, 6–11 months, and 12–59 months) for 2018. The datasets include incidence rates of...
- Subject
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Global Burden of DiseaseGlobal Health/statistics & numerical dataParamyxoviridae InfectionsRespiratory Tract Infections
- Access Rights
- Unrestricted access
- Local Experts
- Karen L. Kotloff
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UMB Dataset
Mobile device data reveal the dynamics in a positive relationship between human mobility and COVID-19 infections
- Authors
- Chenfeng XiongSonghua HuMofeng YangWeiyu Luo1 more author(s)...
- Description
This study uses a computing platform to analyze and estimate the correlation between human mobility and COVID-19 spreading. The infection data are collected from various county, state and national sources and mobile device location data are procured from multiple third-party data providers. To capture the time-varying relationship between the number of infection and mobility inflow, the authors developed...
- Subject
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Computers, HandheldCOVID-19
- Timeframe
- 2020
- Access Rights
- Unrestricted access
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UMB Dataset
Assessment of the Real-World Safety Profile of Vedolizumab Using the United States Food and Drug Administration Adverse Event Reporting System
- Authors
- Raymond K. CrossMichael ChioreanFrancis VekemanYongling Xiao3 more author(s)...
- Description
For two decades the standard drug therapy for patients with Crohn’s disease (CD) and ulcerative colitis (UC) has been anti-tumor necrosis factor agents (anti-TNFs) such as adalimumab (Humira), certolizumab pegol (Cimzia), infliximab (Remicade) and several others. More recently, vedolizumab (Entyvio) has entered the market as the first gut-selective integrin blocker that offers an alternative treatment...
- Subject
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Colitis, Ulcerative/drug therapyCrohn Disease/drug therapyDrug-Related Side Effects and Adverse Reactions
- Access Rights
- Approval required
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UMB Dataset
Adjuvant-containing control arms in pivotal quadrivalent human papillomavirus vaccine trials: restoration of previously unpublished methodology
- Authors
- Peter DoshiFlorence BourgeoisKyungwan HongMark Jones4 more author(s)...
- Description
Randomised, placebo-controlled clinical trials are considered the gold standard for evaluating new vaccines. To assess its efficacy and safety, the manufacturer of quadrivalent human papillomavirus (qHPV) vaccine conducted multiple clinical trials involving approximately 30,000 volunteers. The trials of the qHPV vaccine are reported as ‘placebo-controlled.’ However, participants in the ‘placebo’ arms...
- Subject
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Clinical Trials as Topic/ethicsClinical Trials as Topic/standards
- Access Rights
- Unrestricted accessApproval required