UMB Data Catalog

A project of the Health Sciences and Human Services Library
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Results Found: 5
  • UMB Dataset

    Human Disease Ontology Project

    Authors
    Lynn M. Schriml (Principal Investigator)
    Description

    Human Disease Ontology (DO) Project release files. The DO project actively collaborates with biomedical and clinical researchers and data repositories to coordinate a standardized classification of human disease. The DO's GitHub repository includes the monthly releases (https://tinyurl.com/DiseaseOntologyReleases), of OWL, OBO, JSON and XML formatted files along with DO subsets (ontology slims) for...

    Subject
    Bioinformatics
    Biological Ontologies
    Classification
    Access Rights
    Unrestricted access
  • UMB Dataset

    Global burden of acute lower respiratory infection associated with human parainfluenza virus in children under five years for 2018: a systematic review and meta-analysis

    Authors
    Respiratory Virus Global Epidemiology Network
    Xin Wang
    Harish Nair
    Description

    Through a systematic review, this study collected published and unpublished data on human parainfluenza virus (hPIV) burden to estimate the global and regional number of hPIV-associated acute lower respiratory infections (ALRI) cases, hospitalizations, and mortality by children under five years (stratified 0–5 months, 6–11 months, and 12–59 months) for 2018. The datasets include incidence rates of...

    Subject
    Global Burden of Disease
    Global Health/statistics & numerical data
    Paramyxoviridae Infections
    Respiratory Tract Infections
    Access Rights
    Unrestricted access
    Local Experts
    Karen L. Kotloff
  • UMB Dataset

    Mobile device data reveal the dynamics in a positive relationship between human mobility and COVID-19 infections

    Authors
    Chenfeng Xiong
    Songhua Hu
    Mofeng Yang
    Weiyu Luo
    1 more author(s)...
    Description

    This study uses a computing platform to analyze and estimate the correlation between human mobility and COVID-19 spreading. The infection data are collected from various county, state and national sources and mobile device location data are procured from multiple third-party data providers. To capture the time-varying relationship between the number of infection and mobility inflow, the authors developed...

    Subject
    Computers, Handheld
    COVID-19
    Timeframe
    2020
    Access Rights
    Unrestricted access
  • UMB Dataset

    Assessment of the Real-World Safety Profile of Vedolizumab Using the United States Food and Drug Administration Adverse Event Reporting System

    Authors
    Raymond K. Cross
    Michael Chiorean
    Francis Vekeman
    Yongling Xiao
    3 more author(s)...
    Description

    For two decades the standard drug therapy for patients with Crohn’s disease (CD) and ulcerative colitis (UC) has been anti-tumor necrosis factor agents (anti-TNFs) such as adalimumab (Humira), certolizumab pegol (Cimzia), infliximab (Remicade) and several others. More recently, vedolizumab (Entyvio) has entered the market as the first gut-selective integrin blocker that offers an alternative treatment...

    Subject
    Colitis, Ulcerative/drug therapy
    Crohn Disease/drug therapy
    Drug-Related Side Effects and Adverse Reactions
    Access Rights
    Approval required
  • UMB Dataset

    Adjuvant-containing control arms in pivotal quadrivalent human papillomavirus vaccine trials: restoration of previously unpublished methodology

    Authors
    Peter Doshi
    Florence Bourgeois
    Kyungwan Hong
    Mark Jones
    4 more author(s)...
    Description

    Randomised, placebo-controlled clinical trials are considered the gold standard for evaluating new vaccines. To assess its efficacy and safety, the manufacturer of quadrivalent human papillomavirus (qHPV) vaccine conducted multiple clinical trials involving approximately 30,000 volunteers. The trials of the qHPV vaccine are reported as ‘placebo-controlled.’ However, participants in the ‘placebo’ arms...

    Subject
    Clinical Trials as Topic/ethics
    Clinical Trials as Topic/standards
    Access Rights
    Unrestricted access
    Approval required