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  • UMB Dataset

    The heme-responsive PrrH sRNA regulates Pseudomonas aeruginosa pyochelin gene expression

    Authors
    Tra-My Hoang
    Weiliang Huang
    Jonathan Gans
    Jacob Weiner
    5 more author(s)...
    Description

    Bacterial strains, including Pseudomonas aeruginosa, were cultured in media supplemented with iron or heme under different growth conditions, including shaking and static cultures, and exposed to different light conditions (ambient, infrared, dark). For RNA isolation and analysis, cultures were treated with RNA later and processed for quantitative real-time PCR, northern blot analyses, RNA sequencing...

    Subject
    Bacterial Proteins/metabolism
    Access Rights
    Unrestricted access
  • UMB Dataset

    Plasmodium vivax Transcriptomes Reveal Stage-specific Chloroquine Response and Differential Regulation of Male and Female Gametocytes

    Authors
    Adam Kim
    Jean Popovici
    Didier Menard
    David Serre
    Description

    Plasmodium vivax is the most widespread human malaria parasite. However, its biology is little understood for a number of reasons, not the least of which is the inability to continuously propagate it in vitro. Utilizing samples of whole blood taken from 26 Cambodian patients who were determined to be solely infected with the parasite, this research investigated three aspects of P. vivax activity: 1)...

    Subject
    Gene Expression Profiling
    Plasmodium vivax
    Access Rights
    Unrestricted access