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  • UMB Dataset

    mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant

    Authors
    Etsuro Nanishi
    Marisa E. McGrath
    Timothy R. O’Meara
    Soumik Barman
    17 more author(s)...
    Description

    This study investigates multiple vaccine strategies to enhance immunogenicity and protection against SARS-CoV-2 in aged mice. The study aims to determine the effect of a booster dose, with an emphasis on older age. Female three and eleven-month-old BALB/c mice were studied over the course of 38 weeks. Mice received BNT162b2 SARS-CoV-2 spike mRNA vaccine series, primary vaccination series, and mock...

    Subject
    COVID-19/prevention & control
    Viral Vaccines/genetics
    Access Rights
    Unrestricted access
    Local Experts
    Matthew B. Frieman