-
UMB Dataset
Safety, Reactogenicity, and immunogenicity of Inactivated Monovalent Influenza A(H5N1) Virus Vaccine Administered With or Without AS03 Adjuvant
- Authors
- Wilbur H. Chen
- Description
This multicenter randomized, controlled, double-blind Phase 1 trial investigated the safety, tolerability, immunogenicity, and feasibility of adding an adjuvant to an influenza vaccine at point-of-use (commonly referred to as the Mix-N-Match study). Inactivated influenza A/Indonesia/05/2005 virus vaccine and the adjuvant, AS03, were provided by the US Department of Health and Human Services (HHS) Biomedical...
- Subject
-
Vaccines
- Timeframe
- 2011
- Access Rights
- Registration required
-
UMB Dataset
Persistance of Antibody to Influenza A/H5N1 Vaccine Virus: Impact of AS03 Adjuvant
- Authors
- Wilbur H. Chen
- Description
The research associated with this dataset is an extension of a multicenter randomized, controlled, double-blind phase 1 trial that investigated combining an adjuvant (AS03) with an influenza (A/H5N1) vaccine at point-of-use (see “Related Datasets” below). In the original study adult volunteers were given 2 intramuscular doses of vaccine containing 3.75, 7.5, or 15 mcg of hemagglutinin (HA) with or...
- Subject
-
Vaccines
- Access Rights
- Registration required
