UMB Data Catalog
A project of the Health Sciences and Human Services Library-
Osteoarthritis Initiative
- Alternate Title(s)
- OAI
- Description
Four clinical centers participated in this 11 year, prospective observational study of knee osteoarthritis. The goal of the research was to identify biochemical, genetic, and imaging biomarkers associated with the development and progression of osteoarthritis. Evaluation of the cumulative data in comparison with structural and/or clinical outcomes is expected to provide insights into the prevention and treatment of the disease. Over the course of the study, data were collected from 4,796 subjects from over 431,000 clinical and imaging visits resulting in close to 26,626,000 images in the archive. Multiple datasets from this research include: Participant Information (demographic & cohort, measures inventory, outcomes); AllClinical Dataset (multiple datasets with subject risk factors, joint symptom/function, medical history, physical exam, nutrition, & biomarkers (summary of phlebotomy and urine specimen collection times)); Medication Inventory; Knee MR Image Assessments (quantitative cartilage morphometry, semi-quantitative scoring); Knee MRI Metaanalysis; Knee X-Ray Image Assessments; Knee X-Ray Metaanalysis; FNIH Project (post-processed OAI image data as well as serum and urine evaluations from a subset of one of the cohorts); Ancillary Studies (accelerometry measurements, Bone Quality MRI and DEXA measurements, Pivotal OAI MRI Analyses (POMA), and Skin Auto-Fluorescence (Sage) measurements).
- Subject
-
OsteoarthritisOsteoarthritis, KneeOsteoarthritis/epidemiology
- Geographic Coverage
- United States
- Access Rights
- Registration required
- Local Experts
- Qoot Alkhubaizi