UMB Data Catalog

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Results Found: 3
  • UMB Dataset

    Strain-specific alterations in gut microbiome and host immune responses elicited by tolerogenic Bifidobacterium pseudolongum

    Authors
    Bing Ma
    Samuel J. Gavzy
    Vikas Saxena
    Yang Song
    12 more author(s)...
    Description

    To determine strain-specific driving mechanisms of B. pseudolongum UMB-MBP-01, researchers compared it to porcine tropic strain B. pseudolongum ATCC25526 using cell culture and in vivo experimentation and comparative genomic approaches. The data demonstrates that these two strains possess distinct genetic repertoires in carbohydrate assimilation, differential activation signatures and cytokine responses...

    Subject
    Immunity
    Access Rights
    Unrestricted access
  • UMB Dataset

    Kinetics of SARS-CoV-2 antibody responses preCOVID-19 and post-COVID-19 convalescent plasma transfusion in patients with severe respiratory failure: an observational case–control study

    Authors
    Magali J. Fontaine
    Matthew N. Klein
    Elizabeth Wenqian Wang
    Paul Zimand
    8 more author(s)...
    Description

    This observational retrospective control study investigated the development of the humoral immune response to SARS-CoV-2 in convalescent plasma (CCP) recipients (n=34) and compared it to the humoral response in a group of patients not treated with CCP (n=68). Additionally, a separate comparison of clinical outcomes was performed between CCP recipients and a matched control group of untreated patients...

    Subject
    COVID-19
    Immunization, Passive
    Timeframe
    2020
    Access Rights
    Approval required
  • UMB Dataset

    COVID-19 hospitalizations and deaths averted under an accelerated vaccination program in northeastern and southern regions of the USA

    Alternate Title(s)
    COVID-19 Agent Based Model
    Authors
    Thomas N. Vilches
    Pratha Sah
    Seyed M. Moghadas
    Affan Shoukat
    4 more author(s)...
    Description

    An age-stratified agent-based model of COVID-19 was used to simulate outbreaks in states within two U. S. regions. The northeastern region consisted of Connecticut, Massachusetts, Maine, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island and Vermont. The southern region consisted of Alabama, Arkansas, Delaware, District of Columbia, Florida, Georgia, Kentucky, Louisiana, Maryland, Mississippi,...

    Subject
    COVID-19
    Hospitalization
    Immunization Programs
    Access Rights
    Unrestricted access
    Local Experts
    Meagan C. Fitzpatrick