UMB Data Catalog

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Results Found: 3
  • UMB Dataset

    Protection from Cholera with CVD 103-HgR

    Alternate Title(s)
    Efficacy of Single-Dose Live Oral Cholera Vaccine CVD 103-HgR
    Authors
    Wilbur H. Chen
    Myron M. Levine
    Description

    This dataset is the result of a phase 3, randomized, double-blind, placebo-controlled efficacy trial of a single dose live oral cholera vaccine. PXVX0200 was developed to rapidly confer protection to humanitarian relief workers and other travelers visiting cholera-endemic areas as well as residents in regions experiencing outbreaks. Existing licensed vaccines require 2 or 3 (children) doses weeks apart....

    Subject
    Vaccines
    Access Rights
    Approval required
    Registration required
  • UMB Dataset

    Safety, Reactogenicity, and immunogenicity of Inactivated Monovalent Influenza A(H5N1) Virus Vaccine Administered With or Without AS03 Adjuvant

    Authors
    Wilbur H. Chen
    Description

    This multicenter randomized, controlled, double-blind Phase 1 trial investigated the safety, tolerability, immunogenicity, and feasibility of adding an adjuvant to an influenza vaccine at point-of-use (commonly referred to as the Mix-N-Match study). Inactivated influenza A/Indonesia/05/2005 virus vaccine and the adjuvant, AS03, were provided by the US Department of Health and Human Services (HHS) Biomedical...

    Subject
    Vaccines
    Timeframe
    2011
    Access Rights
    Registration required
  • UMB Dataset

    Persistance of Antibody to Influenza A/H5N1 Vaccine Virus: Impact of AS03 Adjuvant

    Authors
    Wilbur H. Chen
    Description

    The research associated with this dataset is an extension of a multicenter randomized, controlled, double-blind phase 1 trial that investigated combining an adjuvant (AS03) with an influenza (A/H5N1) vaccine at point-of-use (see “Related Datasets” below). In the original study adult volunteers were given 2 intramuscular doses of vaccine containing 3.75, 7.5, or 15 mcg of hemagglutinin (HA) with or...

    Subject
    Vaccines
    Access Rights
    Registration required