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Penicillin Skin Testing in Methicillin-Sensitive Staphylococcus aureus Bacteremia: A Cost-Effectiveness Analysis
UMB Dataset

UID: 95

Author(s): Todd Joseph Mattingly, II*, Stephen Meninger, Emily L. Heil * Corresponding Author
Description
Beta-lactams provide superior outcomes in comparison to vancomycin in treating methicillin-susceptible Staphylococcus aureus (MSSA) infections complicated by bacteremia. However, approximately 11% of inpatients report a penicillin (PCN) allergy when it is estimated that only 1% of the general population is truly allergic to the antibiotic. Consequently, many patients may be receiving suboptimal treatment for a serious infection with a high mortality rate. This study evaluated the cost-effectiveness of penicillin skin testing (PST) in adult inpatients self-reporting PCN allergy and undergoing treatment for MSSA bacteremia. A decision analytic model was developed comparing an acute care PST intervention to a scenario with no confirmatory allergy testing. This dataset includes a decision analytic model diagram, model inputs, and an Excel file with MSSA bacteremia model parameters and probabilistic simulation calculations.
Subject Domain
Keywords
Access via Article

Decision analytic model diagram, input table, and results

Access Restrictions
Free to All
Access Instructions
All relevant data are within the paper and its Supporting Information File
Associated Publications
Data Type
Software Used
Microsoft Excel
Study Type
Observational
Dataset Format(s)
Microsoft Excel
Grant Support
Educational Grant/ALK, Inc.
Other Resources
Supplementary File 1 (Excel)

MSSA Bacteremia Parameters