This study was undertaken to investigate the neuropathological mechanisms associated with spinal cord injury (SCI) pain. The research focused on the possible abnormal functional connectivity between the thalamus and cortex believed to be the etiology of SCI pain. A total of 14 rats were included in the research separated into 2 groups: SCI (8) and sham-operated (6). Resting-state functional magnetic resonance imaging scans were performed before surgery and postoperatively at 3, 7, 14, and 21 days. Dataset includes neuroimages and Seed-Based Correlation Analysis values.