This data set consists of the results of a survey developed to examine substance use, psychosocial, and mental health variables in a sample of patients who received a liver transplant and were diagnosed with an alcohol-related liver disease. Participants were asked about their quantity, duration and frequency of alcohol and substance use prior to and following liver transplant. The Alcohol Use Disorders Identification Test (AUDIT), a 10-item measure for at risk drinking, assessed current alcohol consumption for participants who reported any past-year alcohol consumption. The Fagerstrom test assessed nicotine dependence using a six-item measure of nicotine dependence. The Patient Health Questionnaire (PHQ-9)(14) screened for depression symptomatology, and the Generalized Anxiety Disorder (GAD-7), a seven-item measure that assesses symptoms of worry and anxiety over the past two weeks (15) was used to screen for anxiety symptoms. The Interpersonal Support Evaluation List (ISEL-12) was used as a measure of social support. Other survey items included questions on demographic variables (i.e., marital status, employment, residency, history of incarceration) as well as substance use and mental health service utilization. Age, race/ethnicity, Model for End-Stage Liver Disease (MELD) score, insurance status, and transplant wait list time were extracted from patient medical records. A total of 67 individuals were surveyed.