Clinical decision support (CDS) is a method to streamline the complexity of genomic medicine. Researchers conducted an in-depth evaluation of implementation strategies across a network focused on implementing genomic medicine, called Implementing Genomics In Practice, to gather data on common strategies for applying provider-based CDS interventions. The first phase used a web-based, self-administered, 15 minute structured survey derived from a typology of implementation strategies, the Expert Recommendations for Implementing Change (ERIC). The structured survey was used to gather information on implementation strategies used at sites. Follow-up interviews, guided by both implementation strategy reporting criteria and a planning framework, RE-AIM, obtained more detail about implementation strategies and desired outcomes.