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Analysis of Rickettsia typhi-Infected and Uninfected Cat Flea (Ctenocephalides felis) Midgut cDNA Libraries: Deciphering Molecular Pathways Involved in Host Response to R. typhi Infection
- Authors
- Abdu F. AzadSheila M. Dreher-LesnickShane M. CeraulSky C. Lesnick4 more author(s)...
- Description
Murine typhus is a febrile disease caused by the bacterium, Rickettsia typhi (R. typhi), and transmitted via infected fleas. This study investigated midgut responses of infected versus uninfected cat fleas (Ctenocephalides felis) by constructing cDNA libraries and examining transcript levels. Select C. felis serine proteases, GTPases and defense response genes were compared to identify differences...
- Subject
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CtenocephalidesGene Expression ProfilingRickettsia typhiTranscription, Genetic
- Timeframe
- 2009
- Access Rights
- Unrestricted access