UMB Data Catalog
A project of the Health Sciences and Human Services Library-
Assessing Muscle-Related Adverse Events in Randomized Trials of Statins
UMB Dataset- Authors
- Peter DoshiKyungwan HongSarah TanveerTom Jefferson
- Description
This study examined randomized trials of statins to investigate the reporting of muscle-related adverse events (MRAEs). The study highlights the importance of critical appraisal of trial design and data collection methods from clinical study reports. Internal company trial documents were requested from the European Medicines Agency and Health Canada for all clinical trials of atorvastatin, rosuvastatin, fluvastatin, and simvastatin. 25 of the 85 trails obtained and screened for documents met the inclusion criteria for assessment.
- Subject
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Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects
- Geographic Coverage
- International
- Access Rights
- Unrestricted access