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Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM)

Alternate Titles(s): AFFIRM

UID: 53

The AFFIRM clinical trial was instituted to compare the impact on total mortality between two treatment strategies for managing atrial fibrillation (AF): maintenance of sinus rhythm (includes control of heart rate) and control of heart rate alone. Anticoagulation was used with both treatments. 4060 patients from over 200 sites in the U.S. and Canada participated in the study. All enrollees had AF and at least one additional risk factor for stroke or death. Dataset includes patient baseline characteristics, clinical measures, medications, hospitalizations, major adverse events and mortality, and cognitive ability assessments as well as selected quality of life measures.
1995 - 2001
Local Experts
Subject of Study
Subject Domain
Population Age
Senior (65 years to 79 years)
Elderly (80 years and over)
Access Restrictions
Submission of a request via link on the BioLINCC site
Access Instructions
Available to registered users via BioLINCC
Associated Publications
Study Type