UMB Data Catalog
A project of the Health Sciences and Human Services LibraryInitial findings from a novel population-based child mortality surveillance approach: a descriptive study
UMB Dataset
Alternate Titles(s): Child Health and Mortality Prevention and Surveillance Network (CHAMPS)
UID: 112
- Description
- The Child Health and Mortality Prevention and Surveillance Network (CHAMPS) includes data from sites in sub-Saharan Africa and south Asia, with the joint goal of generating and accumulating more precise, detailed, and robust data on causes of child mortality in locations across these regions with high child mortality. Deaths of stillbirths, neonates, and children ages 1 to 59 months (< 5 years) were investigated using a variety of methodologies, including minimally invasive tissue sampling (MITS), a post-mortem approach using biopsy needles for sampling key organs and body fluids, which has been validated as an acceptable proxy method to complete diagnostic autopsy for cause of death ascertainment. Molecular testing, classical microbiology, histopathology, and immunohistochemistry were used to assess samples obtained from MITS. Additionally, verbal autopsy was used and antemortem clinical data was collected. In-country panels of experts analyzed each death using all available data and determined the most plausible sequence and causes of death. In this study, the contribution of these methods for detailing cause of death data is demonstrated at a level of granularity previously unavailable in LMICs (low income and middle income countries) and the high acceptance rate for the MITS procedure in a range of LMIC settings is shown. The study describes the first insights regarding the advantages of this approach for under-5 mortality surveillance, which could highlight potential pathways to prevent child mortality. UMB participation in this study: Karen L. Kotloff and Milagritos D. Tapia (Department of Pediatrics, Center for Vaccine Development and Global Health and Division of Infectious Disease and Tropical Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA) are co-authors of the article on this study and Carol L. Greene, J. Kristie Johnson, Rima Koka, Ashka Mehta, Sharon M. Tennant (University of Maryland School of Medicine, Baltimore, MD, USA) are members of The Champs Consortium. CHAMPS data is available online. Data specific to this study is also included in the article and its Supplementary Material.
- Timeframe
- 2016 - 2018
- Geographic Coverage
-
BangladeshKenyaMaliMozambiqueSouth Africa
Child (2 years to 12 years)
Infant (1 to 23 months of age)
Infant, Newborn (first 28 days after birth)
- Access Restrictions
-
Unrestricted access
- Access Instructions
- Summarized data openly avaiable on CHAMPS website. All other data requires to register and request data. Data specific to this study is also included in the article and its Supplementary Material.
- Associated Publications
- PubMed Search
- View articles which use this dataset
- Data Type
- Equipment Used
-
Custom TaqMan Array Cards
- Software Used
- Study Type
-
Empirical Research
- Data Collection Instruments
-
2016 WHO Verbal Autopsy Instrument
- Dataset Size
- 993 subject to MITS
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