Sleep, circadian rhythms and fatigue in children with CNS tumors hospitalized for high dose chemotherapy

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Sleep, circadian rhythms and fatigue in children with CNS tumors hospitalized for high dose chemotherapy

UID: 88

Author(s): Valerie E. Rogers*, Belinda Mandrell

* Corresponding Author

Description: This study tested a sleep promotion intervention (randomized controlled trial) in children with recently diagnosed central nervous system tumors admitted to the hospital for high dose chemotherapy in preparation for autologous stem cell rescue. We hypothesized that disturbed sleep of hospitalized pediatric oncology patients would be reduced by altering the hospital sleep environment. Therefore, a randomized, attention-controlled sleep intervention was implemented in children and adolescents with central nervous system tumors admitted for 6 days for high dose chemotherapy prior to stem cell transplant. Children and adolescents diagnosed with medulloblastoma or histologically similar tumor, 4 to 19 years and their parent were recruited over 3 years.Questionnaires used to gather the data were: Fatigue Scale-Child, Fatigue Scale-Adolescent, Fatigue Scale-Parent. Data was also obtained using actigraphy.
Timeframe: 2008 - 2011
Geographic Coverage: Memphis (Tenn.)

Subject of Study

Subject Domain

Central Nervous System/Cancer

Sleep Wake Disorders

Population Age

Child (2 years to 12 years)

Adolescent (13 years to 18 years)

Subject Gender

Female

Male

Keywords

Circadian Activity Rhythm

Randomized Controlled Trials as Topic