UMB Data Catalog
A project of the Health Sciences and Human Services Library-
Immunologic Response to ART by Age Among Treatment-Naive Patients in Sub-Saharan Africa
UMB Dataset- Alternate Title(s)
- Immunologic Response to Antiretroviral Therapy by Age Among Treatment-Naive Patients in Sub-Saharan Africa
- Authors
- Kristen A. StaffordLaurence S. MagderLaura L. HungerfordJack M. Guralnik3 more author(s)...
- Description
This study investigated the association of age with CD4+ cell counts of HIV patients receiving antiretroviral treatment (ART) over a 4 year period. Data were collected from 126,672 previously treatment-naïve patients in 4 Sub-Saharan African nations. The baseline CD4+ count was measured at onset of ART and at 6-month intervals thereafter. The predictor variable was the age at initiation of therapy with ages grouped in five 10-year ranges: 20-29, 30-39, 40-49, 50-59, and 60 and over. The following 8 baseline covariates were also noted: sex, WHO stage, functional status, active TB infection, active cryptococcal disease, active P. jiroveci pneumonia, other active opportunistic infections, and ART regimen. The resulting dataset includes 466,482 repeated CD4+ count measurements with demographic and other patient-related characteristics.
- Subject
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HIV Infections
- Geographic Coverage
- International