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  • UMB Dataset

    Transcriptomic comparisons of macroscopically normal-appearing and scarred lung tissues in idiopathic pulmonary fibrosis

    Authors
    Sergei P. Atamas
    Description

    Idiopathic pulmonary fibrosis (IPF) produces scarring in the peripheral and basilar regions of the lung with macroscopically normal-appearing tissue in the central and apical areas. This study involved comparing transcriptomic profiles of the latter with transcriptomes of scarred IPF and healthy control lung tissues. The primary goal of the research was to elucidate the pathobiology of the disease...

    Subject
    Gene Expression Profiling
    Sequence Analysis
    Access Rights
    Unrestricted access
  • UMB Dataset

    Neuropeptide identification using eyestalk-RNAseq of red deep-sea crab, Chaceon quenquedens

    Authors
    Shadaesha Green
    Tsvetan Bachvaroff
    J. Sook Chung
    Description

    This study aimed to understand the role of eyestalk neuropeptides in vitellogenesis. Molt-inhibiting hormone (MIH) and crustacean hyperglycemic hormone (CHH) cDNA sequences were first isolated from the eyestalk ganglia of C. quinquedens using traditional cloning methods and their expression was quantified in the eyestalk ganglia at various ovarian stages. De novo transcriptome assembly of the eyestalk...

    Subject
    Brachyura/genetics
    Invertebrate Hormones/genetics
    Neuropeptides
    Access Rights
    Unrestricted access