UMB Data Catalog

A project of the Health Sciences and Human Services Library
of 1 Next >
Results Found: 2
  • UMB Dataset

    Analysis of Rickettsia typhi-Infected and Uninfected Cat Flea (Ctenocephalides felis) Midgut cDNA Libraries: Deciphering Molecular Pathways Involved in Host Response to R. typhi Infection

    Authors
    Abdu F. Azad
    Sheila M. Dreher-Lesnick
    Shane M. Ceraul
    Sky C. Lesnick
    4 more author(s)...
    Description

    Murine typhus is a febrile disease caused by the bacterium, Rickettsia typhi (R. typhi), and transmitted via infected fleas. This study investigated midgut responses of infected versus uninfected cat fleas (Ctenocephalides felis) by constructing cDNA libraries and examining transcript levels. Select C. felis serine proteases, GTPases and defense response genes were compared to identify differences...

    Subject
    Ctenocephalides
    Gene Expression Profiling
    Rickettsia typhi
    Transcription, Genetic
    Timeframe
    2009
    Access Rights
    Unrestricted access
  • UMB Dataset

    Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation

    Authors
    Shannon L. Cole
    Ramesh Chandra
    Maya Harris
    Ishan Patel
    8 more author(s)...
    Description

    This dataset was generated to investigate long-lasting neurobiological adaptations to drugs of abuse. This dataset specifically supported the study of cocaine exposure impact of mitochondrial dynamics and morphology through early growth response factor 3 (Egr3) transcriptional regulation of mitochondria-related nuclear gene transcripts. Mitochondria-related nuclear genes were assayed following contingent...

    Subject
    Cocaine/pharmacology
    Early Growth Response Protein 3
    Mitochondrial Dynamics
    Neurons
    Transcription, Genetic/drug effects
    Access Rights
    Unrestricted access
    Approval required