This dataset consists of comparisons of mortality and hospital discharge rates/diagnoses between Old Order Amish (OOA) living in Lancaster County, Pennsylvania, and non-Amish Caucasians. The Anabaptist Genealogy Database Version 5 (AGDB5) and the Framingham Heart Study (FHS) were utilized for the mortality statistics for each cohort, respectively. Additionally, OOA health-related data were collected from hospital discharge records from 4 Lancaster County hospitals while the National Hospital Discharge Survey (NHDS) was used for non-Amish Caucasians. For each discharge the principal diagnosis and up to 6 additional diagnoses were recorded using ICD-9-CM codes. The dataset consists of demographics, mortality statistics, hospital discharge and diagnoses data, as well as longevity and health-related comparison analyses between the two groups.
Diabetes, hypertension, and hypercholesterolemia are three of the major risk factors for the development of cardiovascular disease (CVD), a leading cause of death in the United States. The burden of these disorders is not uniform across the country primarily due to socioeconomic status, cultural practices, and lifestyle. To evaluate the effect of these disparities, this study compared the prevalence of the 3 conditions in a subpopulation in the US with that of the general population. The Old Order Amish (OOA) community located in rural Pennsylvania is characterized by distinctive sociocultural practices that include a very cohesive social structure and limited use of modern technologies and medication. A total of 5377 OOA individuals took part in a community-wide survey which included a physical exam and fasting blood draw. The prevalence of the 3 risk factors in the Amish was then compared to the European Caucasian subsample of the 2013–2014 US National Health and Nutrition Examination Survey (NHANES). This dataset includes demographics, physical examination values, medication history, clinical measures associated blood pressure, cholesterol, and glucose, and statistical assessment and comparison data.
The Amish Research Group of the University of Maryland School of Medicine has been studying the Old Order Amish population in Lancaster County, PA, since 1993. This database currently consists of health-related data on over 7,000 adults resulting from studies ranging from population and basic science to clinical and translational research. Areas of investigation include: Cardiovascular Risk, Diabetes, Bone Health, Blood Pressure, Vascular Imaging, Aging, Breast Tissue Density, Platelet Aggregation, Microbiome, Wellness, and Brain Imaging. Extensive genetic data (genotyping and sequencing) is also available.