Residents from 13 community-based nursing homes located in Maryland and Michigan participated in this study of MRSA transmission rates to healthcare personnel (HCP) during routine care activities. Upon enrollment, cultures were taken at the anterior nares and perianal skin. Of the 401 participants, 113 were MRSA colonized. A random sample of non-colonized residents were also included in the study. HCP gloves and gowns were swabbed after each interaction with participants and the activity type and duration recorded. This dataset includes resident characteristics (demographics, health status, etc.) type of care activity, and transmission rates.
Beta-lactams provide superior outcomes in comparison to vancomycin in treating methicillin-susceptible Staphylococcus aureus (MSSA) infections complicated by bacteremia. However, approximately 11% of inpatients report a penicillin (PCN) allergy when it is estimated that only 1% of the general population is truly allergic to the antibiotic. Consequently, many patients may be receiving suboptimal treatment for a serious infection with a high mortality rate. This study evaluated the cost-effectiveness of penicillin skin testing (PST) in adult inpatients self-reporting PCN allergy and undergoing treatment for MSSA bacteremia. A decision analytic model was developed comparing an acute care PST intervention to a scenario with no confirmatory allergy testing. This dataset includes a decision analytic model diagram, model inputs, and an Excel file with MSSA bacteremia model parameters and probabilistic simulation calculations.
The dataset contains data pertaining to the examination of draft genomes of 388 methicillin-resistant Staphylococcus aureus isolates obtained from intensive care unit patients at three geographically distributed hospitals. The purpose of the study was to determine genomic diversity associated with potential health care worker-associated transmission. Relevant statistics, including linked GenBank and SRA accession numbers for each genome assembly, are included in Table 1 of the associated publication.